EAK proteins: novel conserved regulators of C. elegans lifespan
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چکیده
منابع مشابه
EAK proteins: novel conserved regulators of C. elegans lifespan
FoxO transcription factors (TFs) extend lifespan in invertebrates and may participate in the control of human longevity. The role of FoxO TFs in lifespan regulation has been studied most extensively inC. elegans, where a conserved insulin/insulin-like growth factor signaling (IIS) pathway and the germline both control lifespan by regulating the subcellular localization of the FoxO transcription...
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ژورنال
عنوان ژورنال: Aging
سال: 2010
ISSN: 1945-4589
DOI: 10.18632/aging.100214